Article List
List all articles in the database by earliest discovery_date
GET /articles/?format=api&page=1429
{ "count": 24864, "next": "http://api.gregory-ms.com/articles/?format=api&page=1430", "previous": "http://api.gregory-ms.com/articles/?format=api&page=1428", "results": [ { "article_id": 431030, "title": "Large granular lymphocytic leukemia cured by allogeneic stem cell transplant: a case report", "summary": "<jats:title>Abstract</jats:title><jats:sec>\n <jats:title>Background</jats:title>\n <jats:p>Large granular lymphocytic leukemia is a rare lymphocytic neoplasm that can pose a treatment challenge in patients with severe neutropenia in whom conventional therapies fail. We report one of the first cases in which allogeneic stem cell therapy was used as treatment for large granular lymphocytic leukemia.</jats:p>\n <jats:p>We report and discuss the case of a 42-year-old white Caucasian female who, despite multiple therapies including methotrexate, cyclophosphamide, prednisone, cyclosporine, and pentostatin, continued to show severe neutropenia and recurrent infections. The patient was treated successfully and cured by allogeneic stem cell transplant without any major complications.</jats:p>\n </jats:sec><jats:sec>\n <jats:title>Conclusions</jats:title>\n <jats:p>The significant importance of this case report is the introduction of a new treatment algorithm for challenging cases of T-cell large granular lymphocytic leukemia in which standard care fails. We hope that this case report will raise awareness of the potential benefits of allogeneic stem cell transplant in the treatment of aggressive forms of T-cell large granular lymphocytic leukemia.</jats:p>\n </jats:sec>", "link": "https://jmedicalcasereports.biomedcentral.com/articles/10.1186/s13256-022-03447-y", "published_date": "2022-06-07T23:00:00Z", "sources": [ "BioMedCentral" ], "teams": [ { "id": 1, "name": "Team Gregory" } ], "subjects": [ { "subject_name": "Multiple Sclerosis", "description": null } ], "publisher": "Springer Science and Business Media LLC", "container_title": "Journal of Medical Case Reports", "authors": [ { "author_id": 309205, "given_name": "Edward", "family_name": "Carey", "ORCID": null, "country": null }, { "author_id": 309206, "given_name": "Nicholas", "family_name": "Ward", "ORCID": null, "country": null }, { "author_id": 228539, "given_name": "Maher", "family_name": "Abdul-Hay", "ORCID": "http://orcid.org/0000-0003-1041-7689", "country": null } ], "relevant": null, "ml_prediction_gnb": false, "ml_prediction_lr": false, "ml_prediction_lsvc": false, "discovery_date": "2022-06-08T06:44:40.977628Z", "noun_phrases": [ "allogeneic stem cell transplant" ], "doi": "10.1186/s13256-022-03447-y", "access": "open", "takeaways": " Large granular lymphocytic leukemia poses challenge in patients with severe neutropenia in whom conventional therapies fail . The patient was treated successfully and cured by allogeneic stem cell transplant without any major complications . The significant importance of this case report is the introduction of a new treatment algorithm .", "categories": [] }, { "article_id": 430712, "title": "Digital tools for the assessment of pharmacological treatment for depressive disorder: State of the art", "summary": "Depression is an invalidating disorder, marked by phenotypic heterogeneity. Clinical assessments for treatment adjustments and data-collection for pharmacological research often rely on subjective representations of functioning. Better phenotyping through digital applications may add unseen information and facilitate disentangling the clinical characteristics and impact of depression and its pharmacological treatment in everyday life. Researchers, physicians, and patients benefit from...", "link": "https://pubmed.ncbi.nlm.nih.gov/35671641/?fc=20210216052009&ff=20220608014821&v=2.17.6", "published_date": "2022-06-07T10:00:00Z", "sources": [ "PubMed" ], "teams": [ { "id": 1, "name": "Team Gregory" } ], "subjects": [ { "subject_name": "Multiple Sclerosis", "description": null } ], "publisher": "Elsevier BV", "container_title": "European Neuropsychopharmacology", "authors": [ { "author_id": 229666, "given_name": "Evelien", "family_name": "Van Assche", "ORCID": "http://orcid.org/0000-0003-3472-3031", "country": null }, { "author_id": 309752, "given_name": "J.", "family_name": "Antoni Ramos-Quiroga", "ORCID": null, "country": null }, { "author_id": 157016, "given_name": "Carmine M.", "family_name": "Pariante", "ORCID": "http://orcid.org/0000-0002-9132-5091", "country": "GB" }, { "author_id": 156957, "given_name": "Luca", "family_name": "Sforzini", "ORCID": "http://orcid.org/0000-0001-6795-0391", "country": null }, { "author_id": 156986, "given_name": "Allan H.", "family_name": "Young", "ORCID": "http://orcid.org/0000-0003-2291-6952", "country": "GB" }, { "author_id": 254497, "given_name": "Yanina", "family_name": "Flossbach", "ORCID": null, "country": null }, { "author_id": 157001, "given_name": "Stefan M.", "family_name": "Gold", "ORCID": "http://orcid.org/0000-0001-5188-4799", "country": null }, { "author_id": 309753, "given_name": "Witte J.G.", "family_name": "Hoogendijk", "ORCID": null, "country": null }, { "author_id": 229669, "given_name": "Bernhard T.", "family_name": "Baune", "ORCID": "http://orcid.org/0000-0001-6548-426X", "country": null }, { "author_id": 254491, "given_name": "Eduard", "family_name": "Maron", "ORCID": null, "country": null } ], "relevant": null, "ml_prediction_gnb": false, "ml_prediction_lr": false, "ml_prediction_lsvc": false, "discovery_date": "2022-06-08T05:51:20.877074Z", "noun_phrases": [ "Digital tools", "the assessment", "pharmacological treatment", "depressive disorder", "State", "the art" ], "doi": "10.1016/j.euroneuro.2022.05.007", "access": "open", "takeaways": " Depression is an invalidating disorder, marked by phenotypic heterogeneity . Better phenotyping through digital applications may add unseen information .", "categories": [] }, { "article_id": 430710, "title": "Efficacy of Fluoxetine, Riluzole and Amiloride in treating neuropathic pain associated with secondary progressive multiple sclerosis. Pre-specified analysis of the MS-SMART double-blind randomised placebo-controlled trial", "summary": "CONCLUSION: Use of Fluoxetine, Riluzole or Amiloride was not associated with improvement in neuropathic pain symptoms, in comparison to placebo.", "link": "https://pubmed.ncbi.nlm.nih.gov/35671671/?fc=20210216052009&ff=20220608014821&v=2.17.6", "published_date": "2022-06-07T10:00:00Z", "sources": [ "PubMed" ], "teams": [ { "id": 1, "name": "Team Gregory" } ], "subjects": [ { "subject_name": "Multiple Sclerosis", "description": null } ], "publisher": "Elsevier BV", "container_title": "Multiple Sclerosis and Related Disorders", "authors": [ { "author_id": 198360, "given_name": "Peter", "family_name": "Foley", "ORCID": "http://orcid.org/0000-0001-7039-2976", "country": null }, { "author_id": 276897, "given_name": "Richard A", "family_name": "Parker", "ORCID": null, "country": null }, { "author_id": 294384, "given_name": "Floriana", "family_name": "de Angelis", "ORCID": null, "country": null }, { "author_id": 149994, "given_name": "Peter", "family_name": "Connick", "ORCID": "http://orcid.org/0000-0002-3892-8037", "country": "GB" }, { "author_id": 149995, "given_name": "Siddharthan", "family_name": "Chandran", "ORCID": "http://orcid.org/0000-0001-6827-1593", "country": null }, { "author_id": 282955, "given_name": "Carolyn", "family_name": "Young", "ORCID": null, "country": null }, { "author_id": 182544, "given_name": "Christopher J", "family_name": "Weir", "ORCID": "http://orcid.org/0000-0002-6494-4903", "country": null }, { "author_id": 148223, "given_name": "Jeremy", "family_name": "Chataway", "ORCID": "http://orcid.org/0000-0001-7286-6901", "country": null } ], "relevant": null, "ml_prediction_gnb": false, "ml_prediction_lr": false, "ml_prediction_lsvc": false, "discovery_date": "2022-06-08T05:51:20.872724Z", "noun_phrases": [ "Efficacy", "Fluoxetine", "Riluzole", "Amiloride", "neuropathic pain", "secondary progressive multiple sclerosis", "Pre-specified analysis", "the MS-SMART double-blind randomised placebo-controlled trial" ], "doi": "10.1016/j.msard.2022.103925", "access": "open", "takeaways": "", "categories": [] }, { "article_id": 430709, "title": "Implementing education: Personal communication with a healthcare professional is a critical step to address vaccine hesitancy for people with multiple sclerosis", "summary": "CONCLUSION: Our study highlights that vaccination efforts should be delivered by healthcare professionals, focus on educating those who are managed with DMTs, and include individual recommendations related to specific DMTs, how the vaccines work, expectations regarding potential side-effects, potential exacerbation of MS symptoms, likelihood of recovery from any exacerbation, and the relative risks of side effects versus COVID-19 infection. Specific recommendations are provided.", "link": "https://pubmed.ncbi.nlm.nih.gov/35671672/?fc=20210216052009&ff=20220608014821&v=2.17.6", "published_date": "2022-06-07T10:00:00Z", "sources": [ "PubMed" ], "teams": [ { "id": 1, "name": "Team Gregory" } ], "subjects": [ { "subject_name": "Multiple Sclerosis", "description": null } ], "publisher": "Elsevier BV", "container_title": "Multiple Sclerosis and Related Disorders", "authors": [ { "author_id": 224395, "given_name": "M.G.", "family_name": "Panisset", "ORCID": "http://orcid.org/0000-0002-8353-4061", "country": null }, { "author_id": 306979, "given_name": "T.", "family_name": "Kilpatrick", "ORCID": null, "country": null }, { "author_id": 306980, "given_name": "L.E.", "family_name": "Cofré Lizama", "ORCID": null, "country": null }, { "author_id": 306981, "given_name": "M.P.", "family_name": "Galea", "ORCID": null, "country": null } ], "relevant": null, "ml_prediction_gnb": false, "ml_prediction_lr": false, "ml_prediction_lsvc": false, "discovery_date": "2022-06-08T05:51:20.870463Z", "noun_phrases": [ "education", "Personal communication", "a healthcare professional", "a critical step", "vaccine hesitancy", "people", "multiple sclerosis" ], "doi": "10.1016/j.msard.2022.103933", "access": "open", "takeaways": " Vaccinations should be delivered by healthcare professionals, focus on educating those who are managed with DMTs . Specific recommendations are provided .", "categories": [] }, { "article_id": 430708, "title": "Quantification of upper limb dysfunction in the activities of the daily living in persons with multiple sclerosis", "summary": "CONCLUSIONS: UL dysfunction is highly prevalent in PwMS, even when global disability is mild. BBT and FNT are time-efficient and cost-effective measures that complement the NHPT for more precise monitoring of PwMS at all disease stages.", "link": "https://pubmed.ncbi.nlm.nih.gov/35671673/?fc=20210216052009&ff=20220608014821&v=2.17.6", "published_date": "2022-06-07T10:00:00Z", "sources": [ "PubMed" ], "teams": [ { "id": 1, "name": "Team Gregory" } ], "subjects": [ { "subject_name": "Multiple Sclerosis", "description": null } ], "publisher": "Elsevier BV", "container_title": "Multiple Sclerosis and Related Disorders", "authors": [ { "author_id": 167248, "given_name": "Marco", "family_name": "Pisa", "ORCID": "http://orcid.org/0000-0001-9409-6864", "country": null }, { "author_id": 254621, "given_name": "Jennifer A.", "family_name": "Ruiz", "ORCID": null, "country": null }, { "author_id": 166219, "given_name": "Gabriele C.", "family_name": "DeLuca", "ORCID": "http://orcid.org/0000-0003-0342-5197", "country": null }, { "author_id": 298976, "given_name": "Marta", "family_name": "de Andres Crespo", "ORCID": null, "country": null }, { "author_id": 183751, "given_name": "Heather M.", "family_name": "DelMastro", "ORCID": "http://orcid.org/0000-0003-3373-2518", "country": null }, { "author_id": 298977, "given_name": "Kayla M.", "family_name": "Olson", "ORCID": null, "country": null }, { "author_id": 298978, "given_name": "Elizabeth W.", "family_name": "Triche", "ORCID": null, "country": null }, { "author_id": 254626, "given_name": "Albert C.", "family_name": "Lo", "ORCID": null, "country": null } ], "relevant": null, "ml_prediction_gnb": false, "ml_prediction_lr": false, "ml_prediction_lsvc": false, "discovery_date": "2022-06-08T05:51:20.869244Z", "noun_phrases": [ "Quantification", "upper limb dysfunction", "the activities", "persons", "multiple sclerosis" ], "doi": "10.1016/j.msard.2022.103917", "access": "restricted", "takeaways": "", "categories": [] }, { "article_id": 430707, "title": "Biomarker panel increases accuracy for identification of an MS relapse beyond sNfL", "summary": "CONCLUSION: Our studies confirmed that sNfL is elevated during relapses in RRMS patients. Furthermore, we identified three other blood proteins, uPA, hK8 and DSG3 that were altered during relapse. Together, these four biomarkers could be used to monitor disease activity in RRMS patients.", "link": "https://pubmed.ncbi.nlm.nih.gov/35671674/?fc=20210216052009&ff=20220608014821&v=2.17.6", "published_date": "2022-06-07T10:00:00Z", "sources": [ "PubMed" ], "teams": [ { "id": 1, "name": "Team Gregory" } ], "subjects": [ { "subject_name": "Multiple Sclerosis", "description": null } ], "publisher": "Elsevier BV", "container_title": "Multiple Sclerosis and Related Disorders", "authors": [ { "author_id": 236226, "given_name": "Gaurav", "family_name": "Kumar", "ORCID": "http://orcid.org/0000-0001-5464-6518", "country": null }, { "author_id": 302646, "given_name": "Kaylea", "family_name": "Massey", "ORCID": null, "country": null }, { "author_id": 302647, "given_name": "Andrew", "family_name": "Nguyen", "ORCID": null, "country": null }, { "author_id": 211491, "given_name": "Yang", "family_name": "Mao-Draayer", "ORCID": "http://orcid.org/0000-0001-6248-3480", "country": null }, { "author_id": 302648, "given_name": "Susan", "family_name": "Macwana", "ORCID": null, "country": null }, { "author_id": 302649, "given_name": "Wade", "family_name": "DeJager", "ORCID": null, "country": null }, { "author_id": 302650, "given_name": "Joel M.", "family_name": "Guthridge", "ORCID": null, "country": null }, { "author_id": 187485, "given_name": "Gabriel", "family_name": "Pardo", "ORCID": "http://orcid.org/0000-0002-2207-3708", "country": null }, { "author_id": 247787, "given_name": "Jeffrey", "family_name": "Dunn", "ORCID": null, "country": null }, { "author_id": 236227, "given_name": "Robert C.", "family_name": "Axtell", "ORCID": "http://orcid.org/0000-0001-6041-4588", "country": null }, { "author_id": 302642, "given_name": "Saurabh", "family_name": "Gawde", "ORCID": null, "country": null }, { "author_id": 302643, "given_name": "Agnieshka", "family_name": "Agasing", "ORCID": null, "country": null }, { "author_id": 302644, "given_name": "Neal", "family_name": "Bhatt", "ORCID": null, "country": null }, { "author_id": 302645, "given_name": "Mackenzie", "family_name": "Toliver", "ORCID": null, "country": null } ], "relevant": null, "ml_prediction_gnb": false, "ml_prediction_lr": false, "ml_prediction_lsvc": false, "discovery_date": "2022-06-08T05:51:20.867747Z", "noun_phrases": [ "Biomarker panel", "accuracy", "identification", "an MS relapse", "sNfL" ], "doi": "10.1016/j.msard.2022.103922", "access": "open", "takeaways": "", "categories": [] }, { "article_id": 430706, "title": "Sociodemographic characteristics and emergency department visits and inpatient hospitalizations for atopic dermatitis in Ontario: a cross-sectional study", "summary": "BACKGROUND: Some jurisdictions experience sociodemographic disparities in atopic dermatitis care, including emergency department visits, but data from Canada are limited. Our objectives were to estimate the prevalence of atopic dermatitis in Ontario and to identify sociodemographic factors associated with emergency department visits and hospitalizations for this condition.", "link": "https://pubmed.ncbi.nlm.nih.gov/35672041/?fc=20210216052009&ff=20220608014821&v=2.17.6", "published_date": "2022-06-07T10:00:00Z", "sources": [ "PubMed" ], "teams": [ { "id": 1, "name": "Team Gregory" } ], "subjects": [ { "subject_name": "Multiple Sclerosis", "description": null } ], "publisher": "CMA Impact Inc.", "container_title": "CMAJ Open", "authors": [ { "author_id": 245364, "given_name": "Aaron M.", "family_name": "Drucker", "ORCID": null, "country": null }, { "author_id": 267790, "given_name": "Li", "family_name": "Bai", "ORCID": null, "country": null }, { "author_id": 212116, "given_name": "Lihi", "family_name": "Eder", "ORCID": "http://orcid.org/0000-0002-1473-1715", "country": null }, { "author_id": 267791, "given_name": "An-Wen", "family_name": "Chan", "ORCID": null, "country": null }, { "author_id": 267792, "given_name": "Elena", "family_name": "Pope", "ORCID": null, "country": null }, { "author_id": 253642, "given_name": "Karen", "family_name": "Tu", "ORCID": null, "country": null }, { "author_id": 267793, "given_name": "Liisa", "family_name": "Jaakkimainen", "ORCID": null, "country": null } ], "relevant": null, "ml_prediction_gnb": false, "ml_prediction_lr": false, "ml_prediction_lsvc": false, "discovery_date": "2022-06-08T05:51:20.865698Z", "noun_phrases": [ "Sociodemographic characteristics", "emergency department visits", "inpatient hospitalizations", "atopic dermatitis", "Ontario", "a cross-sectional study" ], "doi": "10.9778/cmajo.20210194", "access": "open", "takeaways": "", "categories": [] }, { "article_id": 430705, "title": "Ofatumumab Modulates Inflammatory T Cell Responses and Migratory Potential in Patients With Multiple Sclerosis", "summary": "BACKGROUND AND OBJECTIVES: The anti-CD20 antibody ofatumumab is an efficacious therapy for multiple sclerosis (MS) through depletion of B cells. The purpose of this study was to examine the derivative effects of B cell depletion on the peripheral immune system and a direct treatment effect on T cells expressing CD20.", "link": "https://pubmed.ncbi.nlm.nih.gov/35672145/?fc=20210216052009&ff=20220608014821&v=2.17.6", "published_date": "2022-06-07T10:00:00Z", "sources": [ "PubMed" ], "teams": [ { "id": 1, "name": "Team Gregory" } ], "subjects": [ { "subject_name": "Multiple Sclerosis", "description": null } ], "publisher": "Ovid Technologies (Wolters Kluwer Health)", "container_title": "Neurology - Neuroimmunology Neuroinflammation", "authors": [ { "author_id": 160390, "given_name": "Marina Rode", "family_name": "von Essen", "ORCID": "http://orcid.org/0000-0001-9367-5020", "country": null }, { "author_id": 160391, "given_name": "Rikke Holm", "family_name": "Hansen", "ORCID": "http://orcid.org/0000-0001-8729-6075", "country": null }, { "author_id": 258617, "given_name": "Camilla", "family_name": "Højgaard", "ORCID": null, "country": null }, { "author_id": 160393, "given_name": "Cecilie", "family_name": "Ammitzbøll", "ORCID": "http://orcid.org/0000-0002-1274-2277", "country": "DK" }, { "author_id": 160394, "given_name": "Heinz", "family_name": "Wiendl", "ORCID": "http://orcid.org/0000-0003-4310-3432", "country": null }, { "author_id": 160395, "given_name": "Finn", "family_name": "Sellebjerg", "ORCID": "http://orcid.org/0000-0002-1333-9623", "country": null } ], "relevant": null, "ml_prediction_gnb": false, "ml_prediction_lr": false, "ml_prediction_lsvc": false, "discovery_date": "2022-06-08T05:51:20.863397Z", "noun_phrases": [ "Ofatumumab Modulates Inflammatory T Cell Responses", "Migratory Potential", "Patients", "Multiple Sclerosis" ], "doi": "10.1212/NXI.0000000000200004", "access": "open", "takeaways": "", "categories": [ { "category_id": 39, "category_description": "ofatumumab, Kesimpta", "category_name": "Ofatumumab", "category_slug": "ofatumumab", "category_terms": [ "ofatumumab", "kesimpta" ], "article_count": 47 } ] }, { "article_id": 430704, "title": "Do patients' and referral centers' characteristics influence multiple sclerosis phenotypes? Results from the Italian multiple sclerosis and related disorders register", "summary": "BACKGROUND: Multiple sclerosis (MS) is characterized by phenotypical heterogeneity, partly resulting from demographic and environmental risk factors. Socio-economic factors and the characteristics of local MS facilities might also play a part.", "link": "https://pubmed.ncbi.nlm.nih.gov/35672479/?fc=20210216052009&ff=20220608014821&v=2.17.6", "published_date": "2022-06-07T10:00:00Z", "sources": [ "PubMed" ], "teams": [ { "id": 1, "name": "Team Gregory" } ], "subjects": [ { "subject_name": "Multiple Sclerosis", "description": null } ], "publisher": "Springer Science and Business Media LLC", "container_title": "Neurological Sciences", "authors": [ { "author_id": 158743, "given_name": "Roberto", "family_name": "Bergamaschi", "ORCID": "http://orcid.org/0000-0002-1397-511X", "country": null }, { "author_id": 154765, "given_name": "Ettore", "family_name": "Beghi", "ORCID": "http://orcid.org/0000-0003-2542-0469", "country": null }, { "author_id": 205246, "given_name": "Cristina", "family_name": "Bosetti", "ORCID": "http://orcid.org/0000-0003-2090-4608", "country": null }, { "author_id": 158736, "given_name": "Michela", "family_name": "Ponzio", "ORCID": "http://orcid.org/0000-0001-5245-0474", "country": "IT" }, { "author_id": 205247, "given_name": "Claudia", "family_name": "Santucci", "ORCID": "http://orcid.org/0000-0002-9845-5307", "country": null }, { "author_id": 205248, "given_name": "Vito", "family_name": "Lepore", "ORCID": "http://orcid.org/0000-0002-5466-780X", "country": null }, { "author_id": 205249, "given_name": "Paola", "family_name": "Mosconi", "ORCID": "http://orcid.org/0000-0003-0415-3744", "country": "IT" }, { "author_id": 265139, "given_name": "U.", "family_name": "Aguglia", "ORCID": null, "country": null }, { "author_id": 244040, "given_name": "M. P.", "family_name": "Amato", "ORCID": null, "country": null }, { "author_id": 298235, "given_name": "A. 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